anti-YBX2 antibody product blog
Tags: Antibody; Polyclonal Antibody; YBX2; anti-YBX2 antibody;
The YBX2 ybx2 (Catalog #MBS625965) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The YBX2, CT (Y-box-binding Protein 2, Germ Cell-specific Y-box-binding Protein, Contrin, MSY2 Homolog, DNA-binding Protein C, Dbpc) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s YBX2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC).Suitable for use in ELISA, Western Blot, and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Western Blot: 1:50-1:100
Immunohistochemistry: 1:10-1:50. Researchers should empirically determine the suitability of the YBX2 ybx2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The YBX2 ybx2 product has the following accession number(s) (GI #156415990) (NCBI Accession #NP_057066.2) (Uniprot Accession #Q9Y2T7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the YBX2, CT (Y-box-binding Protein 2, Germ Cell-specific Y-box-binding Protein, Contrin, MSY2 Homolog, DNA-binding Protein C, Dbpc) with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of YBX2 Antibody (C-term) in Jurkat cell line lysates (35ug/lane). YBX2 (arrow) was detected using the purified Pab.)
Immunohistochemistry (IHC) (Formalin-fixed and paraffin-embedded human testis tissue reacted with YBX2 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.)
YBX2 is a major constituent of messenger ribonucleoprotein particles (mRNPs). It is nvolved in the regulation of the stability and/or translation of germ cell mRNAs. It binds to Y-box consensus promoter element and to full length mRNA with high affinity in a sequence-independent manner. It binds to short RNA sequences containing the consensus site 5\'-UCCAUCA-3\' with low affinity and limited sequence specificity. Its binding with maternal mRNAs is necessary for its cytoplasmic retention. YBX2 may mark specific mRNAs (those transcribed from Y-box promoters) in the nucleus for cytoplasmic storage, thereby linking transcription and mRNA storage/translational delay.
Immunogen: Synthetic peptide selected from the C-terminal region of human YBX2 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing YBX2 are readily searchable from our website. Different antibodies against the same target such as YBX2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.