anti-VEGF antibody product blog
Tags: Antibody; VEGF; Polyclonal Antibody; anti-VEGF antibody;
The VEGF vegfa (Catalog #MBS534840) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The VEGF antibody (biotin) reacts with Human VEGF and may cross-react with other species as described in the data sheet. MyBioSource\'s VEGF can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB).ELISA: 0.25-1 ug/ml
WB: 0.1-0.2 ug/ml. Researchers should empirically determine the suitability of the VEGF vegfa for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The VEGF vegfa product has the following accession number(s) (GI #181971) (NCBI Accession #AAA35789.1) (Uniprot Accession #P15692). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Goat polyclonal VEGF antibody (biotin) conjugated.
Biological Significance: VEGF is a potent growth and angiogenic cytokine. It stimulates proliferation and survival of endothelial cells, and promotes angiogenesis and vascular permeability. Expressed in vascularized tissues, VEGF plays a prominent role in normal and pathological angiogenesis. Substantial evidence implicates VEGF in the induction of tumor metastasis and intra-ocular neovascular syndromes. VEGF signals through the three receptors; fms-like tyrosine kinase (flt-1), kDaR gene product (the Mouse homolog of kDaR is the flk-1 gene product) and the flt4 gene product. Tag/Conjugate: Biotin
Immunogen: VEGF antibody (biotin) was raised in goat using highly pure recombinant human VEGF as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing VEGF are readily searchable from our website. Different antibodies against the same target such as VEGF may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone, Embryonic Tissue, Eye, Heart, Kidney, Liver, Lung, Muscle, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene. VEGF also interacts with the following gene(s): FLT1, HIF1A, IGF1, KDR, MMP9, NRP1, PGF, SRC, TGFB1, VWF. Choroidal Neovascularization, Diabetic Retinopathy, Heart Diseases, Inflammation, Lung Diseases, Macular Degeneration, Macular Edema, Neoplasm Metastasis, Neovascularization, Pathologic, Retinal Diseases are some of the diseases may be linked to VEGF antibody (biotin).