|The USP29 usp29 (Catalog #MBS625646) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The USP29, NT (Ubiquitin Carboxyl-terminal Hydrolase 29, Ubiquitin Thiolesterase 29, Ubiquitin-specific Processing Protease 29, Deubiquitinating Enzyme 29) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s USP29 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Immunohistochemistry (IHC).
Suitable for use in ELISA and Immunohistochemistry.
Dilution: ELISA: 1:1,000
Immunohistochemistry: 1:50-1:100. Researchers should empirically determine the suitability of the USP29 usp29 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The USP29 usp29 product has the following accession number(s) (GI #10190742) (NCBI Accession #NP_065954.1) (Uniprot Accession #Q9HBJ7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Modification of target proteins by ubiquitin participates in a wide array of biological functions. Proteins destined for degradation or processing via the 26 S proteasome are coupled to multiple copies of ubiquitin. However, attachment of ubiquitin or ubiquitin-related molecules may also result in changes in subcellular distribution or modification of protein activity. An additional level of ubiquitin regulation, deubiquitination, is catalyzed by proteases called deubiquitinating enzymes, which fall into four distinct families. Ubiquitin C-terminal hydrolases, ubiquitin-specific processing proteases (USPs),1 OTU-domain ubiquitin-aldehyde-binding proteins, and Jab1/Pad1/MPN-domain-containing metallo-enzymes. Among these four families, USPs represent the most widespread and represented deubiquitinating enzymes across evolution. USPs tend to release ubiquitin from a conjugated protein. They display similar catalytic domains containing conserved Cys and His boxes but divergent N-terminal and occasionally C-terminal extensions, which are thought to function in substrate recognition, subcellular localization, and protein-protein interactions.
Immunogen: Synthetic peptide selected from the N-terminal region of human USP29 (KLH). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing USP29 are readily searchable from our website. Different antibodies against the same target such as USP29 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain Diseases, Obesity are some of the diseases may be linked to USP29, NT (Ubiquitin Carboxyl-terminal Hydrolase 29, Ubiquitin Thiolesterase 29, Ubiquitin-specific Processing Protease 29, Deubiquitinating Enzyme 29). Testis tissues are correlated with this protein.