anti-TTR antibody product blog
Tags: Antibody; TTR; Polyclonal Antibody; anti-TTR antibody; TTR / Transthyretin;
The TTR ttr (Catalog #MBS241997) is an Antibody produced from TTR/Transthyretin antibody was produced in Goat. and is intended for research purposes only. The product is available for immediate purchase. The Goat Polyclonal to Human TTR / Transthyretin reacts with Human, MonkeyPredicted Reactivity: Bovine, Dog, Pig, Rabbit, Sheep and may cross-react with other species as described in the data sheet. MyBioSource\'s TTR / Transthyretin can be used in a range of immunoassay formats including, but not limited to, IHC
IHC - Paraffin (10 ug/ml)
ELISA (5 - 10 ug/ml)
Peptide Enzyme-Linked Immunosorbent Assay (1:1000)
Optimal dilution to be determined by the researcher). .
. Researchers should empirically determine the suitability of the TTR ttr for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TTR ttr product has the following accession number(s) (GI #4507725) (NCBI Accession #NP_000362.1) (Uniprot Accession #P02766). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat Polyclonal to Human TTR / Transthyretin with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-TTR / Transthyretin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.)
Prealbumin, also known as transethrytin (TTR) is a carrier protein; it transports thyroid hormones in the plasma and cerebrospinal fluid, and also transports retinol (vitamin A) in the plasma. The protein consists of a tetramer of identical subunits. More than 80 different mutations in this gene have been reported; most mutations are related to amyloid deposition, affecting predominantly peripheral nerve and/or the heart, and a small portion of the gene mutations is non-amyloidogenic.
Target: TTR/Transthyretin
Immunogen Description: Synthetic peptide C-YKVEIDTKSYWK from an internal region of human TTR / Transthyretin (NP_000362.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%).
Immunogen Species: TTR/Transthyretin antibody was raised against Human.
Epitope: AA89-100
Antigen Type: Synthetic peptide
Immunogen: TTR / Transthyretin antibody was raised against synthetic peptide C-YKVEIDTKSYWK from an internal region of human TTR / Transthyretin (NP_000362.1). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Orangutan, Gibbon, Monkey (100%); Sheep, Elephant, Panda, Dog, Bovine, Rabbit, Pig (92%); Mouse, Rat, Hamster, Bat, Horse, Platypus (83%).
Antigen Modification: Internal
Usage Summary: Immunohistochemistry: MBS241997 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat inudced antigen retrieval in pH6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for MBS241997 was determined to be 10 ug/ml.