anti-TTN antibody product blog
Tags: Antibody; Monoclonal Antibody; Titin; anti-TTN antibody; TTN;
The TTN ttn (Catalog #MBS607370) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Titin (TTN, Cardiomyopathy Dilated 1G (Autosomal Dominant), CMD1G, CMH9, CMPD4, Connectin, DKFZp451N061, FLJ26020, FLJ26409, FLJ32040, FLJ34413, FLJ39564, FLJ43066, HMERF, LGMD2J, MU-RMS-40.14, Rhabdomyosarcoma Antigen MU RMS 40.14, TMD) reacts with Avian, Chicken, Human, Mammal, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Titin can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).Suitable for use in Electron microscopy, Immunofluorescence, Western Blot and Immunohistochemistry.
Dilution: Western Blot: 1:100-1:2000
Immunohistochemistry (frozen): 1:10-1:2000
Electron microscopy: 1:10-1:500
Immunofluorescence (IC): 1:1000. Researchers should empirically determine the suitability of the TTN ttn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TTN ttn product has the following accession number(s) (GI #1212992) (Uniprot Accession #Q8WZ42). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Monoclonal Anti-Titin can be used for study of the elastic filaments within sarcomeric structures. It is also useful as a differentiation marker in the separation of rhabdomyosarcomas from other muscle tumors. By indirect immunofluorescence the antibody displays a typical striated staining pattern on frozen sections of chicken skeletal and cardiac muscle tissues. Stains the region of the A-I junction by indirect immunofluorescence. It shows a decoration line 0.05 mm from the end of the A band in electron micro-graphs.In immunoblotting, using total extracts of chicken breast muscle, the antibody reacts specifically with both bands of the titin double and shows no reaction with nebulin.
Immunogen: Full length native Titin (purified) (Chicken breast muscle). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TTN are readily searchable from our website. Different antibodies against the same target such as TTN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TTN also interacts with the following gene(s): CAPN3, FLNA, MYBPC3, NEB, OBSCN, TCAP. The following patways have been known to be associated with this gene.