anti-TTBK2 antibody product blog
Tags: Antibody; Polyclonal Antibody; TTBK2; anti-TTBK2 antibody;
The TTBK2 ttbk2 (Catalog #MBS151356) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TTBK2 Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TTBK2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC).TTBK2 antibody can be used for detection of TTBK2 by immunohistochemistry at 5 mug/mL. Researchers should empirically determine the suitability of the TTBK2 ttbk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TTBK2 ttbk2 product has the following accession number(s) (GI #47940064) (NCBI Accession #AAH71556) (Uniprot Accession #Q6IQ55). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TTBK2 Antibody with the following immunoassay(s):
Immunohistochemistry (IHC) (Immunohistochemistry of TTBK2 in human placenta tissue with TTBK2 antibody at 5 μg/mL.)
TTBK2 Antibody: Tau tubulin kinase (TTBK2) is a serine/threonine kinase whose substrates are thought to include the tau and tubulin proteins. Mutations in the TTBK2 gene cause spinocerebellar ataxia type 11 (SCA11), a neurodegenerative disease characterized by progressive ataxia and atrophy of the cerebellum and brainstem. Recent studies have shown that increased levels of TTBK2 expression in kidney carcinoma and melanoma cell lines increases resistance to the chemotherapeutic agent Sunitinib, and that reduction of TTBK2 though the use of siRNA sensitized these cell lines to the effects of Sunitib, suggesting that TTBK2 can be used as a resistance marker as well a potential target to overcome resistance.
Conjugate: Unconjugated
Immunogen: TTBK2 antibody was raised against an 18 amino acid synthetic peptide near the carboxy terminus of human TTBK2.
Buffer: TTBK2 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TTBK2 are readily searchable from our website. Different antibodies against the same target such as TTBK2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Liver, Lung tissues are correlated with this protein. Brain Diseases, Congenital Abnormalities, Kidney Diseases, Nervous System Diseases, Spinocerebellar Ataxia 11, Spinocerebellar Ataxias are some of the diseases may be linked to TTBK2 Antibody.