|The TSLP tslp (Catalog #MBS150203) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TSLP Antibody reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TSLP can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
TSLP antibody can be used for detection of TSLP by Western blot at 0.5 - 2 mug/mL. Antibody can also be used for immunohistochemistry starting at 2.5 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the TSLP tslp for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TSLP tslp product has the following accession number(s) (GI #14719428) (NCBI Accession #NP_149024) (Uniprot Accession #Q969D9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TSLP Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of TSLP in A-20 cell lysate with TSLP antibody at (A) 0.5, (B) 1 and (C) 2 μg/mL.)
Immunohistochemistry (IHC) (Immunohistochemistry of TSLP in human brain tissue with TSLP antibody at 2.5 μg/mL.)
Immunofluorescence (IF) (Immunofluorescence of TSLP in Human Brain tissues with TSLP antibody at 20 μg/mL.)
TSLP Antibody: Thymic stromal lymphopoietin (TSLP) has recently been identified as an important factor capable of driving dendritic cell maturation and activation. TSLP is a four-helix-bundle cytokine that is expressed mainly by barrier epithelial cells and is a potent activator of several cell types such as myeloid dendritic cells. TSLP is involved in the positive selection of regulatory T cells, maintenance of peripheral CD4+ T cell homeostasis and the induction of CD4+ T cell-mediated allergic reaction. TSLP is also capable of supporting the growth of fetal liver and adult B cell progenitors and their differentiation to the IgM-positive stage of B cell development. Amino acid sequence analysis has shown poor homology between human and mouse TSLP although they exhibit similar biological functions and are expressed in similar tissues. At least two differentially spliced isoforms of TSLP are known to exist.
Immunogen: TSLP antibody was raised against a 19 amino acid synthetic peptide from near the center of human TSLP.
Buffer: TSLP Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TSLP are readily searchable from our website. Different antibodies against the same target such as TSLP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.