anti-TSC2 antibody product blog
Tags: Antibody; Polyclonal Antibody; TSC2; anti-TSC2 antibody; Tuberin / TSC2;
The TSC2 tsc2 (Catalog #MBS240302) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human Tuberin / TSC2 reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Tuberin / TSC2 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Immunocytochemistry (ICC), Western Blot (WB).ICC, IHC-P (5 ug/ml), WB (1 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.. Researchers should empirically determine the suitability of the TSC2 tsc2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TSC2 tsc2 product has the following accession number(s) (GI #116256352) (NCBI Accession #NP_000539.2) (Uniprot Accession #P49815). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human Tuberin / TSC2 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-TSC2 / Tuberin antibody IHC of human pancreas. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Immunofluorescence (IF) (Immunofluorescence of TSC2 in L1210 cells with TSC2 antibody at 20 ug/ml.)
Immunocytochemistry (ICC) (Immunocytochemistry of TSC2 in L1210 cells with TSC2 antibody at 10 ug/ml.)
Western Blot (WB) (Western blot of TSC2 in L1210 cell lysate with TSC2 antibody at (A) 2 and (B) 4 ug/ml.)
Tuberous sclerosis complex (TSC) is an autosomal dominant tumor syndrome caused by mutations in either of the TSC1 or TSC2 tumor suppressor genes. The products of these genes form a protein complex that indirectly decreases the signaling of the mammalian Target of Rapamycin (TOR), an evolutionarily conserved serine/threonine kinase that regulates cell growth and cell cycle through its ability to integrate signals from nutrient levels and growth factors.
Target Species: Human
Immunogen Description: Synthetic peptide from human TSC2. Immunogen Type: Synthetic peptide
Immunogen: Tuberin / TSC2 antibody was raised against synthetic peptide from human TSC2.
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TSC2 are readily searchable from our website. Different antibodies against the same target such as TSC2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.