anti-TPSAB1 antibody product blog
Tags: Antibody; Polyclonal Antibody; Tpsab1; anti-TPSAB1 antibody; tryptase alpha/beta 1;
The TPSAB1 tpsab1 (Catalog #MBS714041) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti-human tryptase alpha/beta 1 polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s tryptase alpha/beta 1 can be used in a range of immunoassay formats including, but not limited to, ELISA,WB. Researchers should empirically determine the suitability of the TPSAB1 tpsab1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The TPSAB1 tpsab1 product has the following accession number(s) (GI #13775595) (NCBI Accession #NP_003285.2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Tryptases comprise a family of trypsin -like serine proteases, the peptidase family S1. Tryptases are enzymatically active only as heparin-stabilized tetramers, and they are resistant to all known endogenous proteinase inhibitors. Several tryptase genes are clustered on chromosome 16p13.3. These genes are characterized by several distinct features. They have a highly conserved 3 UTR and contain tandem repeat sequences at the 5 flank and 3 UTR which are thought to play a role in regulation of the mRNA stability. These genes have an intron immediately upstream of the initiator Met codon, which separates the site of transcription initiation from protein coding sequence. This feature is characteristic of tryptases but is unusual in other genes. The alleles of this gene exhibit an unusual amount of sequence variation, such that the alleles were once thought to represent two separate genes, alpha and beta 1. Beta tryptases appear to be the main isoenzymes expressed in mast cells; whereas in basophils, alpha tryptases predominate. Tryptases have been implicated as mediators in the pathogenesis of asthma and other allergic and inflammatory disorders.
Immunogen: Human TPSAB1
Species: Homo sapiens (Human)
Target Names: TPSAB1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TPSAB1 are readily searchable from our website. Different antibodies against the same target such as TPSAB1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TPSAB1 also interacts with the following gene(s): CPA3, CTSC, RAC1, RAC2, TPSB2. Bone, Bone Marrow, Connective Tissue, Intestine, Kidney, Lung, Nerve, Skin, Stomach, Testis tissues are correlated with this protein.