anti-TPH1 antibody product blog
Tags: Antibody; Polyclonal Antibody; TRYPTOPHAN HYDROXYLASE; anti-TPH1 antibody; TPH1;
The TPH1 tph1 (Catalog #MBS221818) is an Antibody produced from Sheep and is intended for research purposes only. The product is available for immediate purchase. The SHEEP ANTI TRYPTOPHAN HYDROXYLASE reacts with Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s TRYPTOPHAN HYDROXYLASE can be used in a range of immunoassay formats including, but not limited to, Immunohistology Frozen, Western Blot (WB).Western Blot: This item detects a band of approximately 55kDa in human dorsal Raphe nucleus lysates.
Immunohistology - Frozen: Maximum Dilution: 1/1000
Western Blotting: Maximum Dilution: 1/1000. Researchers should empirically determine the suitability of the TPH1 tph1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TPH1 tph1 product has the following accession number(s) (GI #4759248) (NCBI Accession #NP_004170.1) (Uniprot Accession #P17752). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
MBS221818 recognises Tryptophan Hydroxylase (TPH) which catalyses the 5-hydroxylation of tryptophan, in the first stage of indoleamine biosynthesis. Serotonin biosynthesis occurs principally in neurons which originate in the raphe nucleus of the brain, and melatonin synthesis takes place within the pineal gland.
Perservative Stabilisers: 0.09% Sodium Azide
0.01% Bovine Serum Albumin
50% Glycerol. Immunogen: Recombinant rabbit Tryptophan Hydroxylase purified from E Coli.
Buffer Solution: 10mM HEPES pH7.5
Antiserum Preparation: Antisera to tryptophan hydroxylase were raised by repeated immunisations of sheep with highly purified antigen. Purified IgG prepared by affinity chromatography.
Target Species: Human. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TPH1 are readily searchable from our website. Different antibodies against the same target such as TPH1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TPH1 also interacts with the following gene(s): DDC, IDO1, LRP5, PRL. Carcinoma, Cardiovascular Diseases, Heart Diseases, Hypertension, Hypertension, Pulmonary, Immune System Diseases, Inflammation, Necrosis, Nervous System Diseases, Schizophrenia are some of the diseases may be linked to SHEEP ANTI TRYPTOPHAN HYDROXYLASE. The following patways have been known to be associated with this gene. Brain, Eye, Intestine, Lung, Pituitary Gland tissues are correlated with this protein.