|The LIGHT tnfsf14 (Catalog #MBS535705) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The LIGHT antibody reacts with Human LIGHT and may cross-react with other species as described in the data sheet. MyBioSource\'s LIGHT can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Inhibition, Western Blot (WB). Researchers should empirically determine the suitability of the LIGHT tnfsf14 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The LIGHT tnfsf14 product has the following accession number(s) (GI #397745991) (NCBI Accession #AFO63170.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Rabbit polyclonal LIGHT antibody.
Biological Significance: LIGHT belongs to the TNF family of ligands, and can signal through the herpes virus entry mediator type A receptor (HVEM, TNFRSF14), LTbetaR, or bind to a decoy receptor, DcR3. It is expressed in splenocytes, activated PBL, CD+8 tumor infiltrating lymphocytes, granulocytes, and monocytes. LIGHT has the ability to active NF kb, to co-stimulate the activation of lymphocytes and to induce apoptosis in certain human tumor cells. Immunogen: LIGHT antibody was raised in rabbit using highly pure recombinant human LIGHT as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing LIGHT are readily searchable from our website. Different antibodies against the same target such as LIGHT may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.