anti-TNFRSF1A antibody product blog
Tags: Antibody; Monoclonal Antibody; TNFRSF1A; anti-TNFRSF1A antibody;
The TNFRSF1A tnfrsf1a (Catalog #MBS125977) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The TNFRSF1A Monoclonal Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s TNFRSF1A can be used in a range of immunoassay formats including, but not limited to, Immunofluorescence (IF).Recommended Dilutions - IF: 1:50-1:200. Researchers should empirically determine the suitability of the TNFRSF1A tnfrsf1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TNFRSF1A tnfrsf1a product has the following accession number(s) (GI #135959) (NCBI Accession #P19438.1) (Uniprot Accession #P19438). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the TNFRSF1A Monoclonal Antibody with the following immunoassay(s):
Immunofluorescence (IF) (Immunofluorescence analysis of HeLa cells using TNFRSF1A antibody. Blue: DAPI for nuclear staining.)
This gene encodes a member of the TNF receptor superfamily of proteins. The encoded receptor is found in membrane-bound and soluble forms that interact with membrane-bound and soluble forms, respectively, of its ligand, tumor necrosis factor alpha. Binding of membrane-bound tumor necrosis factor alpha to the membrane-bound receptor induces receptor trimerization and activation, which plays a role in cell survival, apoptosis, and inflammation. Proteolytic processing of the encoded receptor results in release of the soluble form of the receptor, which can interact with free tumor necrosis factor alpha to inhibit inflammation. Mutations in this gene underlie tumor necrosis factor receptor-associated periodic syndrome (TRAPS), characterized by fever, abdominal pain and other features. Mutations in this gene may also be associated with multiple sclerosis in human patients.
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 241-455 of human TNFRSF1A (NP_001056.1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TNFRSF1A are readily searchable from our website. Different antibodies against the same target such as TNFRSF1A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Autoimmune Diseases, Cardiovascular Diseases, Disease Models, Animal, Fever, Heart Diseases, Inflammation, Liver Diseases, Multiple Sclerosis, Necrosis, Pain are some of the diseases may be linked to TNFRSF1A Monoclonal Antibody.