anti-TNFRSF13C antibody product blog
Tags: Antibody; Polyclonal Antibody; BAFF Receptor; anti-TNFRSF13C antibody; TNFRSF13C;
The TNFRSF13C tnfrsf13c (Catalog #MBS621885) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The BAFF Receptor (BAFFR, BAFF-R, BAFF Receptor, B Cell-Activating Factor Receptor, BLyS Receptor 3, BR3, CD268, CD268 antigen, MGC138235, Tumor Necrosis Factor Receptor Superfamily Member 13C, TNFRSF13C) reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s BAFF Receptor can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Suitable for use in Western Blot.
Dilution: Western Blot: 0.5-4 ug/ml. Researchers should empirically determine the suitability of the TNFRSF13C tnfrsf13c for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The TNFRSF13C tnfrsf13c product has the following accession number(s) (GI #15208475) (Uniprot Accession #Q5H8V1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Members in the TNF superfamily regulate immune responses and induce apoptosis. A novel member in the TNF family was recently identified by several groups and designated BAFF, BLyS, TALL-1, THANK, and zTNF4. BAFF/BLyS was characterized as a B cell activator since it induced B cell proliferation and immunoglobulin secretion. Two receptors, TACI and BCMA, for BAFF were originally identified. A third receptor was identified recently and designated BAFF-R and BR3 for BLyS receptor 3. Unlike BCMA and TACI, which bind to BAFF and April, BAFF- R/BR3 is specific for BAFF and plays a predominant role in BAFF induced B cell development and survival. BAFF and its receptors are involved in B cell associated autoimmune diseases, and activate NF- B and c-Jun N-terminal kinase.
Immunogen: Synthetic peptide surrounding aa159of mouse BAFF-R. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TNFRSF13C are readily searchable from our website. Different antibodies against the same target such as TNFRSF13C may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. TNFRSF13C also interacts with the following gene(s): TNFSF13B, TRAF3. The following patways have been known to be associated with this gene.