anti-TIM3 antibody product blog
Tags: Antibody; Monoclonal Antibody; TIM3; anti-TIM3 antibody;
The TIM3 n/a (Catalog #MBS520476) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Anti-Mouse TIM3, PE, (clone: 25F.1D6), (rat IgG2ak) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s TIM3 can be used in a range of immunoassay formats including, but not limited to, Flow Cytometry (FC/FACS), Western Blot (WB). Researchers should empirically determine the suitability of the TIM3 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The TIM3 n/a product has the following accession number(s) (GI #18182535) (NCBI Accession #AAL65158.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
anti-mouse Tim-3 (T cell immunoglobulin domain, mucin domain 3) monoclonal antibody reacts with mouse Tim-3. This 281 amino acid type 1 transmembrane protein contains an immunoglobulin and mucin-like domain in its extra-cellular portion and a tyrosine phosphorylation motif in its cytoplasmic portion. Tim-3 is a member of the immunoglobulin super-family and is expressed on Th1 lymphocytes and CD11b+ macrophages. Tim-3 is a T helper type 1 (TH1)-specific molecule that regulates TH1 mediated auto and alloimmune responses and the induction of peripheral immunological tolerance. This antibody has been reported to work in Flow Cytometry and Immunohistochemistry. This FITC conjugated format is especially useful for direct flow cytometry.
Presentation: Biotin/FITC/PE conjugated IgG buffered in PBS, 0.02% NaN3 and EIA grade BSA as a stabilizing protein to bring total protein concentration to 4-5 mg/mL. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing TIM3 are readily searchable from our website. Different antibodies against the same target such as TIM3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.