anti-THRA antibody product blog
Tags: Antibody; THRA; anti-THRA antibody; Polyclonal Antibody; THRA / THR Alpha;
The THRA thra (Catalog #MBS240098) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human THRA / THR Alpha reacts with Gibbon, Gorilla, Human, MonkeyPredicted Reactivity: Horse (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s THRA / THR Alpha can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (10 - 15 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the THRA thra for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The THRA thra product has the following accession number(s) (GI #20127452) (NCBI Accession #NP_003241.2) (Uniprot Accession #P10827). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human THRA / THR Alpha with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-THRA antibody IHC of human surface epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Thyroid hormone receptor alpha (TR alpha), a NR1 Thyroid Hormone-Like Receptor, mediates the diverse actions of thyroid hormone in development, differentiation, and metabolism. Four protein isoforms are encoded by the same TR alpha genomic locus: TR alpha1 (410 aa) (Nakai et al. 1988), TR alpha2 (490 aa) (Nakai et al. 1988), TR deltaalpha1 (~154 aa), and TR deltaalpha2 (~237 aa); however, only TR alpha1 is able to bind the ligand (Lazar et al. 1988).
Target Species: Human
Immunogen Description: Synthetic 16 amino acid peptide from ligand-binding domain of human THRA. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Horse (94%); Hamster (88%); Rat (81%). Immunogen Type: Synthetic peptide
Immunogen: THRA / THR Alpha antibody was raised against synthetic 16 amino acid peptide from ligand-binding domain of human THRA. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey (100%); Horse (94%); Hamster (88%); Rat (81%).
Antigen Modification: Ligand-binding Domain. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing THRA are readily searchable from our website. Different antibodies against the same target such as THRA may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.