anti-THOP1 antibody product blog
Tags: Antibody; Monoclonal Antibody; Thimet Oligopeptidase; anti-THOP1 antibody; THOP1;
The THOP1 thop1 (Catalog #MBS605765) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Thimet Oligopeptidase (TOP, Thimet Oligopeptidase 1, THOP1, EC 3.4.24.15, Endopeptidase 24.15, EP24.15, MP78, MEPD_HUMAN) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Thimet Oligopeptidase can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunocytochemistry (ICC).Suitable for use in Western Blot and Immunocytochemistry. Researchers should empirically determine the suitability of the THOP1 thop1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The THOP1 thop1 product has the following accession number(s) (GI #4507491) (NCBI Accession #NP_003240.1) (Uniprot Accession #P52888). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
A steady-state level of amyloid beta-peptide (Abeta) represents a balance between its biosynthesis from the amyloid precursor protein (APP) through the action of the beta and gamma-secretases and its catabolism by a variety of proteolytic enxymes. Thimet Oligopeptidase (THOP1) has been shown to promote A-beta degradation. It has also been shown to play a role in antigen presentation, metabolism of neuropeptides under 20 amino acids, and cytoplasmic peptide degradation.
Immunogen: A synthetic peptide corresponding to residues 56-72 of human thimet oligopeptidase.
Cellular Localization: Cytoplasmic. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing THOP1 are readily searchable from our website. Different antibodies against the same target such as THOP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. THOP1 also interacts with the following gene(s): AGTR1. The following patways have been known to be associated with this gene. Neurodegenerative Diseases are some of the diseases may be linked to Thimet Oligopeptidase (TOP, Thimet Oligopeptidase 1, THOP1, EC 3.4.24.15, Endopeptidase 24.15, EP24.15, MP78, MEPD_HUMAN). Brain, Heart tissues are correlated with this protein.