anti-SYP antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-SYP antibody; SYP; Synaptophysin;
The SYP syp (Catalog #MBS373039) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Synaptophysin reacts with Human, Dog, Cat and may cross-react with other species as described in the data sheet.The SYP syp product has the following accession number(s) (GI #27764867) (NCBI Accession #NP_003170.1) (Uniprot Accession #P08247). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Synaptophysin with the following immunoassay(s):
Dilution Information
Immunohistochemistry (IHC)
Synaptophysin is a synaptic vesicle glycoprotein weighing 38 kDa. It is present in endocrine cells, the brain, spinal cord, and adrenal glands. It acts as a marker for neuroendocrine cells. Synaptophysin reacts with neuroendocrine cells of human adrenal medulla, carotid body, skin, pituitary, thyroid, lung, pancreas and gastrointestinal mucosa. Positive staining is seen in neurons of the brain, spinal cord, retina, and Paneth\'s cells in the gastrointestinal tract and gastric parietal cells. This antibody identifies normal neuroendocrine cells and neuroendocrine neoplasms. Diffuse, finely-granular cytoplasmic staining is observed and probably correlates with the distribution of the antigen within neurosecretory vesicles. The expression of Synaptophysin is independent of the presence of NSE or other neuroendocrine markers. Synaptophysin is an independent broad-range marker of neural and neuroendocrine differentiation.
Control: Pancreas
Localization: Cytoplasmic. Reactivity Note: Paraffin, Frozen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SYP are readily searchable from our website. Different antibodies against the same target such as SYP may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. SYP also interacts with the following gene(s): GRB2, VAMP2. Blood, Brain, Embryonic Tissue, Eye, Kidney, Liver, Nerve, Pancreas, Placenta, Prostate tissues are correlated with this protein. Adenocarcinoma, Alzheimer Disease, Brain Diseases, Carcinoma, Cardiovascular Diseases, Cell Transformation, Neoplastic, Kidney Diseases, Mental Disorders, Neoplasms, Nervous System Diseases are some of the diseases may be linked to Synaptophysin.