anti-STXBP1 antibody product blog
Tags: Antibody; Polyclonal Antibody; anti-STXBP1 antibody; STXBP1;
The STXBP1 stxbp1 (Catalog #MBS624409) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The STXBP1 (Syntaxin-binding Protein 1, N-Sec1, Protein unc-18 Homolog 1, Unc18-1, Protein unc-18 Homolog A, Unc-18A, p67, UNC18A) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s STXBP1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB). Researchers should empirically determine the suitability of the STXBP1 stxbp1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.The STXBP1 stxbp1 product has the following accession number(s) (GI #73760415) (NCBI Accession #NP_001027392.1) (Uniprot Accession #P61764). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
STXBP1 (Syntaxin-binding protein 1; also p67, Munc18-1, N-Sec1 and Unc18A) is a 67kD member of the SNARE-interacting Sec1/Unc18/STXBP family of proteins. It is expressed in a variety of cells, presumably in those that exhibit granule exocytosis, and likely participates in (synaptic) granule release. Ligands for STXBP1 include STX1A, 2 and 3, and it is possible that STXBP1 both suppresses STX activity, and serves as an anchor for STX-mediated vesicle fusion. Human STXBP1 is 594aa in length. It contains one SEC1 domain (aa41-575). Phosphorylation at Ser313 may stimulate granule release. There is one splice variant that shows a 28aa substitution for aa576-594. This is restricted to neural tissue. Over aa80-226, human and.
Immunogen: STXBP1 (NP_003156.1, 1-603aa) full-length human protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing STXBP1 are readily searchable from our website. Different antibodies against the same target such as STXBP1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adrenal Gland, Brain, Embryonic Tissue, Kidney, Muscle, Nerve, Ovary, Pancreas, Pineal Gland, Testis tissues are correlated with this protein. STXBP1 also interacts with the following gene(s): APBA1, APBA2, CDK5, PLD2, STX1A, SYTL4. Ataxia, Carcinoma, Death, Embryo Loss, Epilepsies, Myoclonic, Hyperglycemia, Mental Disorders, Necrosis, Neoplasms, Schizophrenia are some of the diseases may be linked to STXBP1 (Syntaxin-binding Protein 1, N-Sec1, Protein unc-18 Homolog 1, Unc18-1, Protein unc-18 Homolog A, Unc-18A, p67, UNC18A).