|The Stra6 stra6 (Catalog #MBS540120) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Stra6 Antibody reacts with Human, Monkey and may cross-react with other species as described in the data sheet. MyBioSource\'s Stra6 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunoprecipitation (IP), Western Blot (WB).
Dot Blot: 1:10,000
Western Blot: 1:500. Researchers should empirically determine the suitability of the Stra6 stra6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Stra6 stra6 product has the following accession number(s) (GI #10434086) (NCBI Accession #BAB14122.1) (Uniprot Accession #O70491). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Stra6 Antibody with the following immunoassay(s):
Western Blot (WB)
Affinity Purified Retinoic acid-responsive protein Antibody
May act as a high-affinity cell-surface receptor for the complex retinol-retinol binding protein (RBP/RBP4). Acts by removing retinol from RBP/RBP4 and transports it across the plasma membrane, where it can be metabolized. This mechanism does not depend on endocytosis. Binds to RBP/RBP4 with high affinity.
Immunogen: Synthetic peptide taken within third large intra cytoplasmic loop within amino acid region 450-500 on human Stra6 protein.
Expression: Widely expressed in the embryo. In the adult, is highly expressed in cells that compose blood-organ barriers in the brain (choroid plexus and the brain microvascular), in the eye (retinal pigment epithelium), in testis (the basal layer of the seminiferous epithelium), in the yolk sac, and in the chorioallantoic placenta (at protein level). Also detected in kidney, spleen, and female genital tract; and at lower levels in heart and lung. Molecular Function: Receptor, Receptor activity
Subcellular Location: Cell membarane; Multi-pass membrane protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Stra6 are readily searchable from our website. Different antibodies against the same target such as Stra6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Anophthalmia with pulmonary hypoplasia, Anophthalmos, Cardiovascular Abnormalities, Heart Defects, Congenital, Hernia, Diaphragmatic, Infertility, Female, Inflammation, Intellectual Disability, Lung Diseases, Microphthalmos are some of the diseases may be linked to Stra6 Antibody.