anti-STK39 antibody product blog
Tags: Antibody; Polyclonal Antibody; PDCD5; anti-STK39 antibody; STK39;
The STK39 stk39 (Catalog #MBS150287) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDCD5 Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s PDCD5 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunocytochemistry (ICC).PDCD5 antibody can be used for detection of PDCD5 by Western blot at 2.5 mug/mL. Antibody can also be used for immunocytochemistry starting at 5 mug/mL. Researchers should empirically determine the suitability of the STK39 stk39 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The STK39 stk39 product has the following accession number(s) (GI #115430252) (NCBI Accession #CAG33215) (Uniprot Accession #Q9UEW8). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PDCD5 Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of PDCD5 in Jurkat cell lysate with PDCD5 antibody at 2.5 μg/mL.)
Immunocytochemistry (IHC) (Immunocytochemistry of PDCD5 in Jurkat cells with PDCD5 antibody at 5 μg/mL.)
PDCD5 Antibody: Programmed cell death 5 (PDCD5), a human apoptosis-related protein, is thought to play an early and universal role in apoptosis. PDCD5 is widely expressed and is upregulated in cells undergoing apoptosis, where it translocates rapidly from the cytoplasm to the nucleus. PDCD5 has a compact core structure of low flexibility with two mobile alpha-helices at N-terminal and a flexible unstructured C-terminal region. The charged residues are crucial for the ability of apoptosis-promoting and cell translocation of the protein. PDCD5 can facilitate apoptosis and enhance TAJ/TROY-induced paraptosis-like cell death. PDCD5 may play a dual role in the Tip60 pathway. It interacts with Tip60 and functions as a Tip60 co-activator to promote apoptosis. The nucleotide polymorphisms in the 5\'-upstream region of�PDCD5 affect promoter activity and the susceptibility of a Chinese population to develop chronic myelogenous leukemia and may represent a novel tumor suppressor gene influencing lung cancer.
Conjugate: Unconjugated
Immunogen: PDCD5 antibody was raised against a 13 amino acid synthetic peptide from near the amino terminus of human PDCD5.
Buffer: PDCD5 Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing STK39 are readily searchable from our website. Different antibodies against the same target such as STK39 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.