anti-STAT6 (pY641) antibody product blog
Tags: Antibody; STAT6 (pY641); anti-STAT6 (pY641) antibody;
The STAT6 (pY641) stat6 (Catalog #MBS462172) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit anti Phospho- STAT6 (pTyr 641) reacts with Human, Rat, Mouse, and may cross-react with other species as described in the data sheet. MyBioSource\'s STAT6 (pY641) can be used in a range of immunoassay formats including, but not limited to, ELISA, Western Blot, Immunohistochemistry.Western Blot: 0.1-1 ug/ml
ELISA: 0.01-0.1 ug/ml
Immunoprecipitation: 2-5 ug/ml
Immunohistochemistry: 1:100 ug/ml. Researchers should empirically determine the suitability of the STAT6 (pY641) stat6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The STAT6 (pY641) stat6 product has the following accession number(s) (GI #23397678) (NCBI Accession #NP_003144.3) (Uniprot Accession #P42226). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit anti Phospho- STAT6 (pTyr 641) with the following immunoassay(s):
Testing Data
STAT proteins (Signal transducer and activator of transcription) belong to a family of cytoplasmic transcription factors that can be phosphorylated by a ligand binding to its cell surface receptor. Activation by phosphorylation of STAT6 at tyrosine 641 upon the IL-4 (possibly IL-13) ligand binding to its receptor induces dimerization, nuclear translocation and DNA binding. STAT6 is widely expressed in human tissues. It exhibits elevated expression in peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung, and placenta. STAT6 mediates the IL-4 signal and is essential for the proper development of adaptive immunity.
Antigen Preparation: A synthetic peptide surrounding to the epitope -RGYVP-- with phosphorylation sites at Tyr641 of STAT6 protein from human, mouse and rat origins. Positive Control: HepG2
Cellular Location: Nuclear. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing STAT6 (pY641) are readily searchable from our website. Different antibodies against the same target such as STAT6 (pY641) may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Asthma, Carcinoma, Dermatitis, Atopic, Fibrosis, Inflammation, Intestinal Diseases, Leukemia, Neoplasms, Neoplasms, Experimental, Respiratory Hypersensitivity are some of the diseases may be linked to Rabbit anti Phospho- STAT6 (pTyr 641). The following patways have been known to be associated with this gene.