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anti-SOX4 antibody product blog

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Posted on 2013-08-23 14:40:42 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; SOX4; anti-SOX4 antibody;
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The SOX4 sox4 (Catalog #MBS120428) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse monoclonal antibody Anti-Human SOX4 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SOX4 can be used in a range of immunoassay formats including, but not limited to, Dot Blot (DB), Immunocytochemistry (ICC). Researchers should empirically determine the suitability of the SOX4 sox4 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The SOX4 sox4 product has the following accession number(s) (GI #30179901) (NCBI Accession #NP_003098.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Mouse monoclonal antibody Anti-Human SOX4 with the following immunoassay(s):
Quality Control (Western blot analysis of immunized recombinant protein, using anti-SOX4 monoclonal antibody.)
Quality Control SOX4.

Quality Control #2 (Arrow indicates the region of immunized recombinant protein carrying 50-200 amino acids.)
Quality Control #2 SOX4.

Immunocytochemistry (ICC) (Immunostaining analysis in HeLa cells. HeLa cells were fixed with 4% paraformaldehyde and permeabilized with 0.1% Triton X-100 in PBS. The cells were immunostained with anti-SOX4 mAb. [Lot No.154C4a-2])
Immunocytochemistry (ICC) SOX4.

This intronless gene encodes a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. The encoded protein may act as a transcriptional regulator after forming a protein complex with other proteins, such as syndecan binding protein (syntenin). The protein may function in the apoptosis pathway leading to cell death as well as to tumorigenesis and may mediate downstream effects of parathyroid hormone (PTH) and PTH-related protein (PTHrP) in bone development. The solution structure has been resolved for the HMG-box of a similar mouse protein.[NCBI Entrez Gene Summary.

Preparation: This antibody was purified using protein G column chromatography from culture supernatant of hybridoma cultured in a medium containing bovine IgG-depleted (approximately 95%) fetal bovine serum. Sterility: Filtered through a 0.22 um membrane. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SOX4 are readily searchable from our website. Different antibodies against the same target such as SOX4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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