anti-SOCS1 antibody product blog
Tags: Antibody; Polyclonal Antibody; SOCS1; anti-SOCS1 antibody;
The SOCS1 socs1 (Catalog #MBS242163) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human SOCS1 reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s SOCS1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), ELISA (EIA).ELISA, IHC-P (5 ug/ml), WB (1 - 2 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the SOCS1 socs1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SOCS1 socs1 product has the following accession number(s) (GI #4507233) (NCBI Accession #NP_003736.1) (Uniprot Accession #O15524). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human SOCS1 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-SOCS1 antibody IHC of human brain, cortex. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.)
Western Blot (WB) (Western blot of SOCS1 in Human spleen cell lysate with SOCS1 antibody at (A) 1, (B) 2 and (C) 4 ug/ml.)
SOCS family proteins form part of a classical negative feedback system that regulates cytokine signal transduction. SOCS1 is involved in the negative regulation of cytokines that signal through the JAK/STAT3 pathway. The binding of SOCS1 to JAKs, inhibits their kinase activity. In vitro, SOCS1 also suppresses Tec protein- tyrosine activity. In addition, SOCS1 appears to be a major regulator of signaling by interleukin 6 (IL6) and leukemia inhibitory factor (LIF).
Target Species: Human
Immunogen Description: Synthetic peptide from human SOCS1. Immunogen Type: Synthetic peptide
Immunogen: SOCS1 antibody was raised against synthetic peptide from human SOCS1.
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SOCS1 are readily searchable from our website. Different antibodies against the same target such as SOCS1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adenocarcinoma, Carcinoma, Hepatocellular, Cardiovascular Diseases, Disease Models, Animal, Inflammation, Liver Diseases, Liver Neoplasms, Lung Diseases, Necrosis, Nervous System Diseases are some of the diseases may be linked to Rabbit Polyclonal to Human SOCS1.