anti-SLC6A6 antibody product blog
Tags: Antibody; Polyclonal Antibody; Taurine Transporter; anti-SLC6A6 antibody; SLC6A6;
The SLC6A6 slc6a6 (Catalog #MBS616155) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Taurine Transporter (Tau1, TauT) reacts with Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Taurine Transporter can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).Suitable for use in Immunofluorescence, ELISA, Western Blot and Immunohistochemistry.
Dilution: ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well.
Western Blot: 1-10ug/ml (ECL)
Immunohistochemistry: 2-20ug/ml
Immunofluorescence: 2-20ug/ml. Researchers should empirically determine the suitability of the SLC6A6 slc6a6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SLC6A6 slc6a6 product has the following accession number(s) (GI #799339) (Uniprot Accession #P31641). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Taurine (2-aminoethane sulfonic acid), a beta amino acid with a negatively charged sulfonic group is one of the most abundant amino acids in the brain. It is particularly enriched (millimolar conc.) in excitable tissues, particularly those that generate oxidants. Taurine is produced by cysteine metabolism and obtained from diet as well. It is a chemically inert molecule with a long turnover rate. It is not incorporated into proteins. It is also thought to play a major role in osmoregulation. It is also postulated to play a critical role in neurotransmission, neuromodulation, and membrane stabilization, neuronal differentiation, migration, synaptogenesis, and development. Taurine is transported to various target tissues by Na-dependent high affinity uptake system carried out by two distinct membrane transporter proteins: a high affinity (Km 40uM) taurine transporter (TAU-1 or TAUT-1) and a beta-alanine and taurine transporter protein (Km 4.5uM) known as TAUT-2. Both TAUT-1/2 share significant sequence homology with the GABA and glycine transporters that are characterized by the presence of 12 transmembrane domains. Taurine transporters are found in brain, retina and many other tissues.
Immunogen: Synthetic peptide consisting of 20aa peptide near the carboxy terminal cytoplasmic region of rat TAU-1. Conjugated to KLH. Species sequence homology: mouse; 100%, human, canine-;90% and bovine; 78%. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SLC6A6 are readily searchable from our website. Different antibodies against the same target such as SLC6A6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.