anti-SLC6A3 antibody product blog
Tags: Antibody; Dopamine Transporter; Polyclonal Antibody; anti-SLC6A3 antibody; SLC6A3;
The SLC6A3 slc6a3 (Catalog #MBS534567) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Dopamine Transporter antibody reacts with Human, Dog, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Dopamine Transporter can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC), Western Blot (WB).ELISA: 0.5-1 ug/ml
IHC: 2-10 ug/ml
WB: 1-10 ug/ml. Researchers should empirically determine the suitability of the SLC6A3 slc6a3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SLC6A3 slc6a3 product has the following accession number(s) (GI #7108463) (NCBI Accession #AAC50179.2) (Uniprot Accession #Q01959). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity purified Rabbit polyclonal Dopamine Transporter antibody.
Biological Significance: The dopamine transporter (also known as dopamine active transporter, DAT, SLC6A3) is a membrane-spanning protein that pumps the neurotransmitter dopamine out of the synapse back into cytosol, from which other transporters sequester DA and NE into vesicles for later storage and release. Dopamine reuptake via DAT provides the primary mechanism through which dopamine is cleared from synapses except in the prefrontal cortex, where dopamine uptake via the norepinephrine transporter plays that role. Cross-Reactivity: Human, dog, mouse
Immunogen: Dopamine transporter antibody was raised in rabbit using an 18 amino acid peptide of rat DAT conjugated to KLH. as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SLC6A3 are readily searchable from our website. Different antibodies against the same target such as SLC6A3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Ganglia, Kidney, Lung, Testis, Thymus, Uncharacterized Tissue tissues are correlated with this protein. SLC6A3 also interacts with the following gene(s): CAMK2A, DRD2, DRD4, NEDD4, PICK1, SLC18A2, SNCA. Attention Deficit Disorder with Hyperactivity, Brain Diseases, Cocaine-Related Disorders, Disease Models, Animal, Movement Disorders, Nerve Degeneration, Nervous System Diseases, Parkinson Disease, Parkinsonian Disorders, Schizophrenia are some of the diseases may be linked to Dopamine Transporter antibody. The following patways have been known to be associated with this gene.