|The SLC29A1 slc29a1 (Catalog #MBS6010109) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The ENT1 (Equilibrative Nucleoside Transporter 1, Equilibrative Nitrobenzylmercaptopurine Riboside-sensitive Nucleoside Transporter, Equilibrative NBMPR-sensitive Nucleoside Transporter, Nucleoside Transporter, es-type, Solute Carrier Family 29 Member 1, SLC2 reacts with Monkey, mouse, rat, bat, bovine, canine, hamster, equine, rabbit. and may cross-react with other species as described in the data sheet. MyBioSource\'s ENT1 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC).
Suitable for use in Immunohistochemistry.
Dilution: Immunohistochemistry (Formalin fixed paraffin embedded): 10-12.5ug/ml. Researchers should empirically determine the suitability of the SLC29A1 slc29a1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SLC29A1 slc29a1 product has the following accession number(s) (GI #118582265) (NCBI Accession #NP_001071644.1) (Uniprot Accession #Q99808). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
SLC29A1/ENT1 is a member of the equilibrative nucleoside transporter family. It is widely distributed and has broad substrate specificity. Expression levels in normal tissues vary within the population; in addition, some carcinomas show a decrease expression level of ENT1. An essential component of the action of nucleoside analog drugs used in anticancer therapies is the uptake and movement of drugs across the plasma membrane. ENT1 and other family members mediate this transport and hence expression levels are of interest in terms of treatment choices.
Immunogen: Synthetic peptide corresponding to 15aa from C-terminal domain of human SLC29A1.
Species Sequence Homology: Monkey, mouse, rat, bat, canine, bovine, hamster, equine, rabbit - 100%; Goat, porcine - 93%; Opossum - 87; Chicken, Xenopus - 80%. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SLC29A1 are readily searchable from our website. Different antibodies against the same target such as SLC29A1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Adenocarcinoma, Brain Diseases, Breast Neoplasms, Cardiovascular Diseases, Inflammation, Lung Neoplasms, Neoplasms, Neoplasms, Experimental, Nervous System Diseases, Pancreatic Neoplasms are some of the diseases may be linked to ENT1 (Equilibrative Nucleoside Transporter 1, Equilibrative Nitrobenzylmercaptopurine Riboside-sensitive Nucleoside Transporter, Equilibrative NBMPR-sensitive Nucleoside Transporter, Nucleoside Transporter, es-type, Solute Carrier Family 29 Member 1, SLC2.