anti-Slc1a2 antibody product blog
Tags: Antibody; Polyclonal Antibody; Glutamate Transporter, Glial; anti-Slc1a2 antibody; Slc1a2;
The Slc1a2 slc1a2 (Catalog #MBS616849) is an Antibody produced from Host: Guinea pig; Source: Rat and is intended for research purposes only. The product is available for immediate purchase. The Guinea pig Anti-Glutamate Transporter, Glial reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Glutamate Transporter, Glial can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).Immunohistochemistry (Paraffin): 1:1000-1:4000 Immunohistochemistry: 1:5000-10,000 Western Blot: 1:500 detected GLT-1 on 10ug of mouse brain lysates Optimal dilution to be determined by researcher. Researchers should empirically determine the suitability of the Slc1a2 slc1a2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Slc1a2 slc1a2 product has the following accession number(s) (Uniprot Accession #P31596). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Guinea pig Anti-Glutamate Transporter, Glial with the following immunoassay(s):
Testing Data (Staining of rat trigeminal motor nucleus using MBS616849)
Testing Data (Staining of rat striatum using MBS616849.)
Glutamate transporters (GluT) function to remove L-glutamate (Glu), the primary excitatory neurotransmitter in the mammalian central nervous system (CNS), from the synaptic cleft. By clearing the synapse in this manner Glu can be recycled for later use, the proper diffusion gradient can be maintained and excitotoxicity can be prevented. There have been reports of many different members of a GluT multigene family; GLT1, GLAST, EAAC1 and EAAT2. mRNA has been identified in brain for each of these proteins.
EAAT2 transports L-glutamate and also L- and D-aspartate. It is essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium.
Immunogen: Synthetic peptide corresponding to the C-terminal of rat GLT-1. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Slc1a2 are readily searchable from our website. Different antibodies against the same target such as Slc1a2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene.