|The Slc12a5 slc12a5 (Catalog #MBS617077) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The KCC2 (K, Cl Cotransporter 2) reacts with Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s KCC2 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in Western Blot and ELISA.
Dilution: Western Blot: 1-10ug/ml using Chemiluminescence technique.
ELISA: 1:10,000-1:100,000 using 50-100ng of control peptide/well. Researchers should empirically determine the suitability of the Slc12a5 slc12a5 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The Slc12a5 slc12a5 product has the following accession number(s) (GI #3925714) (Uniprot Accession #Q91V14). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Chloride is a critical component of all living cells. It is also the single most dominant diffusible anion inside of most cells-the others are mostly impermeable organic anions. Since cytoplasmic electroneutrality is maintained under normal physiological environment, changes in cellular chloride level is accompanied by total cell solute content. The cation chloride cotransporters (CCC) protein family is involved in the electroneutral movement of ions across the cell membrane.
Immunogen: An 18aa peptide sequence within the cytoplasmic, N-terminus of rat KCC2 was used to generate anti-KCC2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Slc12a5 are readily searchable from our website. Different antibodies against the same target such as Slc12a5 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Brain, Embryonic Tissue, Spinal Cord tissues are correlated with this protein. The following patways have been known to be associated with this gene. Epilepsy, Liver Diseases, Necrosis, Occupational Diseases, Seizures are some of the diseases may be linked to KCC2 (K, Cl Cotransporter 2).