anti-SERPINA1 antibody product blog
Tags: Antibody; Polyclonal Antibody; SERPINA1; anti-SERPINA1 antibody; a1-Antichymotrypsin;
The SERPINA1 serpina1 (Catalog #MBS626676) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The a1-Antichymotrypsin (Alpha-1-Antichymotrypsin, AACT, ACT, Growth Inhibiting Protein 24, GIG24, Growth Inhibiting Protein 25, GIG25, Serpin Peptidase Inhibitor Clade A (alpha-1 Antiproteinase, Antitrypsin) Member 3, SERPINA3) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s a1-Antichymotrypsin can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunoprecipitation (IP), Immunohistochemistry (IHC).Suitable for use in ELISA, Immunoprecipitation, Immunodiffusion, Western Blot and Immunohistochemistry. Researchers should empirically determine the suitability of the SERPINA1 serpina1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The SERPINA1 serpina1 product has the following accession number(s) (GI #189163542) (NCBI Accession #NP_001121179.1) (Uniprot Accession #P01009). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
a1-Antichymotrypsin (AACT, Alpha1-ACT) is an early-stage acute-phase plasma protein and a serpin that preferentially inactivates chymotrypsin, cathepsin G, and chymase. a1-Antichymotrypsin, a serine protease inhibitor, is tightly associated with amyloid plaques in Alzheimer\'s disease (AD) and in normal-aged human and monkey brain. Regulation of the serine proteases and serine protease inhibitors plays an important role in neuromuscular differentiation. Prostate specific antigen (PSA), a chymotrypsin-like serine protease, is predominantly complexed to a1-Antichymotrypsin. A higher proportion of serum PSA is complexed to a1-Antichymotrypsin in prostate cancer than in benign prostate hyperplasia.
Immunogen: Human alpha1-Antichymotrypsin. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing SERPINA1 are readily searchable from our website. Different antibodies against the same target such as SERPINA1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Carcinoma, Hepatocellular, Cardiovascular Diseases, Inflammation, Liver Cirrhosis, Liver Diseases, Liver Neoplasms, Lung Diseases, Pulmonary Disease, Chronic Obstructive, Pulmonary Emphysema, alpha 1-Antitrypsin Deficiency are some of the diseases may be linked to a1-Antichymotrypsin (Alpha-1-Antichymotrypsin, AACT, ACT, Growth Inhibiting Protein 24, GIG24, Growth Inhibiting Protein 25, GIG25, Serpin Peptidase Inhibitor Clade A (alpha-1 Antiproteinase, Antitrypsin) Member 3, SERPINA3).