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anti-Scl-70 antibody product blog

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Posted on 2015-05-24 16:12:09 by mybiosource_staff
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Tags: Antibody; Monoclonal Antibody; Scl-70; anti-Scl-70 antibody;
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The Scl-70 n/a (Catalog #MBS604187) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Scl-70 (Scleroderma, DNA Topoisomerase I) reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Scl-70 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot. Researchers should empirically determine the suitability of the Scl-70 n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Topoisomerase I changes the topology of DNA via cleavage of single strand only. Suitable for use in DNA conformational analysis and topology as well as DNA repair, drug resistance, cell proliferation and leukemia studies. The double-helical configuration that DNA strands naturally reside in makes them difficult to separate, and yet they must be separated if enzymes are to transcribe the sequences that encode proteins, or if chromosomes are to be replicated. In so-called circular DNA, in which double helical segment is bent around and joined in a circle, the two strands are topologically linked, or knotted. They cannot be separated by any process that does not involve the breaking of strands. Topoisomerases catalyze and guide the unknotting of DNA.

Scl-70 n/a

Immunogen: Full length Scl-70. Epitiope: YFVPPKEDFK. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Scl-70 are readily searchable from our website. Different antibodies against the same target such as Scl-70 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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