|The sCD40L cd40lg (Catalog #MBS660254) is an Antibody and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s sCD40L can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
Human sCD40L immunoassay. All MAbs work in enzyme immunoassays. MAbs can be used for detection of human sCD40L in serum.
All MAbs work in Western blotting, but for best sensitivity we recommend MAbs 2B10 and 30B4.
Recommended pairs for sandwich immunoassay for detection of native sCD40L in human serum (capture-detection):
1H4 - 2A3
10A6 - 2A3
30B4 - 2A3. Researchers should empirically determine the suitability of the sCD40L cd40lg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The sCD40L cd40lg product has the following accession number(s) (GI #4557433) (NCBI Accession #NP_000065.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Clone Note: Hybridoma clones have been derived from hybridization of Sp2/0 myeloma cells with spleen cells of Balb/c mice immunized with recombinant human soluble CD40 Ligand / TRAP Analog conjugates with BSA. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing sCD40L are readily searchable from our website. Different antibodies against the same target such as sCD40L may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. sCD40L also interacts with the following gene(s): CD40, CD86, ICAM1, RELA, TRAF1. Anemia, Autoimmune Diseases, Cardiovascular Diseases, Heart Diseases, Hyper-IgM Immunodeficiency Syndrome, Type 1, Inflammation, Myocardial Infarction, Myocardial Ischemia, Necrosis, Pneumonia are some of the diseases may be linked to Monoclonal mouse anti-soluble CD40 ligand (sCD40L). Blood, Brain, Mixed, Thymus tissues are correlated with this protein.