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anti-scd antibody product blog

Posted on 2015-01-15 12:48:12 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-SCD antibody; SCD; Stearoyl CoA Desaturase 1;
The scd scd (Catalog #MBS618162) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Stearoyl CoA Desaturase 1 (SCD1) reacts with Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Stearoyl CoA Desaturase 1 can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).
Suitable for use in ELISA and Western Blot.
Dilution: ELISA (Direct and indirect): 1:2000-1:5000
Western Blot: 1:2000-1:5000 using ECL
Suggested blocking and dilution buffer is PBST containing 0.05% Tween-20 and 5% skim milk; suggested incubation time is 1 hour at RT. Researchers should empirically determine the suitability of the scd scd for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The scd scd product has the following accession number(s) (GI #38488714) (NCBI Accession #NP_942110.1) (Uniprot Accession #Q804A7). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Stearoyl-CoA desaturase 1 (SCD1) is a key lipogenic enzyme found in the endoplasmic reticulum that catalyzes the conversion of palmitoyl-CoA and stearoyl- CoA to palmitoleoyl-CoA (16:1) and oleoyl-CoA (18:1). Palmitoleate and oleate are the major components of triglycerides, membrane phospholipids and cholesterol esters. SCD1-knockout mice show improved insulin sensitivity and reduced body fat. Disruption of SCD1 in mouse brown adipose tissue strengthens insulin signaling and results in increased translocation of Glut4 to plasma membrane and enhanced uptake of glucose. Further- more, SCD1 is essential for the onset of diet-induced body weight gain and insulin resistance in the liver.

scd scd

Immunogen: Synthetic peptide corresponding to aa 21-33, APPSGNEREKVKT of mouse Stearoyl-CoA desaturase 1 (SCD1). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing scd are readily searchable from our website. Different antibodies against the same target such as scd may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Kidney, Whole Body tissues are correlated with this protein. Anemia, Cardiovascular Diseases, Fatty Liver, Hypertension, Inflammation, Mental Disorders, Myocardial Infarction, Neoplasms, Neurodegenerative Diseases, Pain are some of the diseases may be linked to Stearoyl CoA Desaturase 1 (SCD1).
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