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anti-ROR1 antibody product blog

Posted on 2014-09-29 01:56:05 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; ROR1; anti-ROR1 antibody;
The ROR1 ror1 (Catalog #MBS176117) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Anti-ROR1 antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s ROR1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC) Paraffin. Researchers should empirically determine the suitability of the ROR1 ror1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The ROR1 ror1 product has the following accession number(s) (GI #118572711) (NCBI Accession #Q01973.2) (Uniprot Accession #Q01973). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-ROR1 antibody with the following immunoassay(s):
Testing Data
Testing Data ROR1.

Testing Data #2
Testing Data #2 ROR1.

Description: Rabbit IgG polyclonal antibody for Tyrosine-protein kinase transmembrane receptor ROR1(ROR1) detection. Tested with WB, IHC-P in Human, Mouse, Rat.
Background: ROR1(receptor tyrosine kinase-like orphan receptor 1), also known as neurotrophic tyrosine kinase, receptor-related 1(NTRKR1), Tyrosine-protein kinase transmembrane receptor ROR1, is a member of thereceptor tyrosine kinase-like orphan receptor(ROR) family. NTRKR1 encodes a predicted 937-amino acid protein. A 6-kb NTRKR1 mRNA is expressed strongly in human heart, lung, and kidney, but weakly in the CNS. However, a truncated 2.4-kb mRNA lacking extracellular and transmembrane domains was strongly expressed in fetal and adult CNS and in a variety of human cancers, including those originating from CNS or PNS neuroectoderm. The protein encoded by this gene is a receptor tyrosine kinase that modulates neurite growth in the central nervous system. It is a type I membrane protein and belongs to the ROR subfamily of cell surface receptors.

Immunogen: A synthetic peptide corresponding to a sequence at the C-terminus of human ROR1 (904-918aa NKSQKPYKIDSKQAS), different from the related rat and mouse sequences by one amino acid. Contents: Each vial contains 5mg BSA, 0.9mg NaCl, 0.2mg Na2HPO4, 0.05mg Thimerosal, 0.05mg NaN3.
Reconstitution: Add 0.2ml of distilled water will yield a concentration of 500ug/ml. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing ROR1 are readily searchable from our website. Different antibodies against the same target such as ROR1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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