anti-RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP) antibody product blog
Tags: Antibody; Polyclonal Antibody; RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP); anti-RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP) antibody;
The RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP) n/a (Catalog #MBS614994) is an Antibody produced from Human and is intended for research purposes only. The product is available for immediate purchase. The RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP) reacts with Human and may cross-react with other species as described in the data sheet.This product shows only the RNP precipitate band when tested using double immunodiffusion against bovine spleen extract. The titer obtained will vary with the test system; however, undiluted antibody shows a strong RNP precipitate band.. Researchers should empirically determine the suitability of the RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP) n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
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Heterogeneous nuclear ribonucleoproteins (hnRNP) bind to nascent RNA polymerase II transcripts and are involved in transcript-specific packaging as well as alternative splicing of pre-mRNAs. hnRNPs also appear to influence mRNA metabolism and transport. In vivo, the M proteins bind to mRNA, and in vitro they bind avidly to poly(G) and poly(U) homopolymers. Four different isoforms of hnRNP are produced by alternative splicing: M1, M2, M3, and M4. Ongoing studies have theorized that hnRNPs may cause certain genetic diseases such as myotonic dystrophy, which is the most common form of adult muscular dystrophy. The identification of hnRNPs may therefore be important to determining the cause and cure for genetic diseases.
Delipidized and defibrinated gamma fraction from a single donor.
Immunogen: RNP Antigen. Autoantibody derived from donor human serum. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP) are readily searchable from our website. Different antibodies against the same target such as RNP M1-M4 Nuclear Ribonucleoprotein, nRNP, hnRNP) may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.