anti-RANKL antibody product blog
Tags: Antibody; RANKL; Monoclonal Antibody; anti-RANKL antibody;
The RANKL tnfsf11 (Catalog #MBS531988) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The RANKL antibody reacts with Human RANKL and may cross-react with other species as described in the data sheet. MyBioSource\'s RANKL can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA),.ELISA: 1.0-2.0ug/ml. Researchers should empirically determine the suitability of the RANKL tnfsf11 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The RANKL tnfsf11 product has the following accession number(s) (GI #2612922) (NCBI Accession #AAB86811.1) (Uniprot Accession #O14788). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Mouse monoclonal RANKL antibody.
Biological Significance: RANKL and RANK are members of the TNF superfamily of ligands and receptors that play an important role in the regulation of specific immunity and bone turnover. RANK (receptor) was originally identified as a dendritic-cell-membrane protein, which by interacting with RANKL augments the ability of dendritic cells to stimulate na. Immunogen: RANKL antibody was raised in mouse using highly pure recombinant human sRANK ligand as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing RANKL are readily searchable from our website. Different antibodies against the same target such as RANKL may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Alveolar Bone Loss, Breast Neoplasms, Cardiovascular Diseases, Inflammation, Necrosis, Neoplasm Metastasis, Osteolysis, Osteopetrosis, Osteoporosis, Pain are some of the diseases may be linked to RANKL antibody. RANKL also interacts with the following gene(s): CTSK, FOS, PTH, PTHLH, SOST, SRC, STAT3, TNFRSF11A, TNFRSF11B, TRAF6. Brain, Connective Tissue, Liver, Lymph Node, Pancreas tissues are correlated with this protein. The following patways have been known to be associated with this gene.