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anti-PTN antibody product blog

Posted on 2014-07-12 08:58:40 by mybiosource_staff
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Tags: Antibody; PTN; Polyclonal Antibody; anti-PTN antibody; Pleiotrophin/PTN;
The PTN ptn (Catalog #MBS422267) is an Antibody produced from Goat and is intended for research purposes only. The product is available for immediate purchase. The Goat anti-Pleiotrophin/PTN Antibody reacts with Tested: Human; Expected from sequence similarity: Human, Mouse, Rat, Dog, Cow, Pig and may cross-react with other species as described in the data sheet. MyBioSource\'s Pleiotrophin/PTN can be used in a range of immunoassay formats including, but not limited to, Peptide ELISA (EIA), Western Blot (WB).
Peptide ELISA: Antibody detection limit dilution 1: 64000.
Western Blot: Approx 18kDa band observed in Mouse and Rat Brain lysates (calculated MW of 18.9kDa according to Human NP_002816.1 and to Mouse NP_032999.1). Recommended concentration: 0.1-0.3ug/ml. Researchers should empirically determine the suitability of the PTN ptn for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The PTN ptn product has the following accession number(s) (GI #4506281) (NCBI Accession #NP_002816.1). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful. The amino acid sequence is listed below:

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Goat anti-Pleiotrophin/PTN Antibody with the following immunoassay(s):
Western Blot (WB) ((0.3ug/ml) staining of Rat Brain lysate (35ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.)
Western Blot (WB) PTN.

Immunogen: Peptide with sequence CGKLTKPKPQAESKK, from the internal region (near C Terminus) of the protein sequence according to NP_002816.1.
Epitope: Internal region (near C Terminus). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PTN are readily searchable from our website. Different antibodies against the same target such as PTN may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. PTN also interacts with the following gene(s): ALK, FGFR1, FYN, KDR, PTEN, PTPRZ1, SDC1, SDC3, SRC. The following patways have been known to be associated with this gene. Bone, Brain, Embryonic Tissue, Heart, Kidney, Liver, Lung, Muscle, Skin, Vascular tissues are correlated with this protein. Carcinoma, Carcinoma, Squamous Cell, Disease Models, Animal, Heart Diseases, Inflammation, Kidney Diseases, Liver Diseases, Lung Neoplasms, Necrosis, Neoplasms, Experimental are some of the diseases may be linked to Goat anti-Pleiotrophin/PTN Antibody.
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