|The Prostaglandin D Synthase, Hematopoietic form n/a (Catalog #MBS601438) is an Antibody produced from Rat and is intended for research purposes only. The product is available for immediate purchase. The Prostaglandin D Synthase, Hematopoietic form (PGD Synthase) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Prostaglandin D Synthase, Hematopoietic form can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC).
Suitable for use in Immunohistochemistry and Western Blot.
Dilution: Immunohistochemistry: 1:1000-1:5000
Western Blot: 1:1000. Incubate for 1 hour at RT.
Optimal dilution determined by the researcher. Researchers should empirically determine the suitability of the Prostaglandin D Synthase, Hematopoietic form n/a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Prostaglandin D synthase (PGD synthase) catalyzes the isomerization of PGH2 to produce PGD2. PGD2 induces sleep, regulates nociception, inhibits platelet aggregation, and acts as an allergic mediator. Two distinct types of PGD synthase have been identified, namely the lipocalin-type enzyme (-trace) and the hematopoietic enzyme. Lipocalin-type PGD synthase is localized in the central nervous system and male genital organs of various mammals and the human heart. This enzyme has been identified as beta-trace, which is a major protein in human cerebrospinal fluid. Hematopoietic PGD synthase is widely distributed in the peripheral tissues and is localized in the antigen-presenting cells, mast cells, and megakaryocytes. This enzyme, which requires glutathione for activity, belongs to the sigma-class of glutathione S-transferases and is approximately 23kD in size.
Immunogen: Recombinant mouse hematopoietic prostaglandin D synthase (H-PGDS). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing Prostaglandin D Synthase, Hematopoietic form are readily searchable from our website. Different antibodies against the same target such as Prostaglandin D Synthase, Hematopoietic form may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.