|The PRG2 prg2 (Catalog #MBS530470) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Eosinophil Major Basic Protein Antibody reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s Eosinophil Major Basic can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Immunohistochemistry (IHC) Paraffin, Western Blot (WB). Researchers should empirically determine the suitability of the PRG2 prg2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PRG2 prg2 product has the following accession number(s) (GI #306839) (NCBI Accession #AAA35965.1) (Uniprot Accession #P13727). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
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Mouse monoclonal Eosinophil Major Basic Protein Antibody.
Biological Significance: Structurally the major basic protein (MBP) is similar to lectins (sugar-binding proteins), and has a fold similar to that seen in C-type lectins. Two crystallographic structures of MBP have been determined. This protein may be involved in antiparasitic defense mechanisms as a cytotoxin and helminthotoxin, and in immune hypersensitivity reactions. It is directly implicated in epithelial cell damage, exfoliation, and bronchospasm in allergic diseases. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling.
Immunogen: Eosinophil major basic protein antibody was raised in mouse using human eosinophil major basic protein as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PRG2 are readily searchable from our website. Different antibodies against the same target such as PRG2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Blood, Bone Marrow, Connective Tissue, Heart, Intestine, Placenta, Vascular tissues are correlated with this protein. Carcinoma, Chromosome Aberrations, Fibrosis, Hypertension, Immune System Diseases, Inflammation, Kidney Diseases, Lung Diseases, Lung Neoplasms, Ovarian Neoplasms are some of the diseases may be linked to Eosinophil Major Basic Protein Antibody. PRG2 also interacts with the following gene(s): AGT, MBP, PAPPA. The following patways have been known to be associated with this gene.