anti-PPARgamma antibody product blog
Tags: Antibody; Polyclonal Antibody; PPARgamma; anti-PPARgamma antibody;
The PPARgamma pparg (Catalog #MBS440118) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPARgamma (C15) Antibody reacts with Mouse, rat, human, hamster, chicken, dog, bovine, pig and may cross-react with other species as described in the data sheet. MyBioSource\'s PPARgamma can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).Recommended for western blotting, starting dilution 1:400. Researchers should empirically determine the suitability of the PPARgamma pparg for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PPARgamma pparg product has the following accession number(s) (GI #20336229) (NCBI Accession #NP_056953.2) (Uniprot Accession #P37231). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Peroxisome proliferator-activated receptors (PPAR) are members of the steroid nuclear receptor superfamily (1). The mammalian PPARs include three subtypes PPARalpha, PPARbeta, and PPARgamma. PPARs have been found to regulate fatty acid oxidation, fat cell development, lipoprotein metabolism, and glucose homeostasis (2). Recent studies have found that PPARs can affect the pathogenesis and development of tumors (3). PPARgamma and PPARbeta have been specifically implicated in tumorigenesis (3). PPARalpha is the focus of research studying its function in fatty acid beta-oxidation, lipid metabolism, and vascular inflammation (4). PPARbeta also plays a key role in the activation of keratinocytes during the inflammatory reaction associated with a skin injury (5). Of the three subtypes of PPARs, PPARgamma is the most widely studied. PPARgamma has been implicated in various human chronic diseases such as diabetes mellitus, atherosclerosis, rheumatoid arthritis, inflammatory bowel disease, and Alzheimer�s disease (6).
Origin: PPARgamms (C15) is provided as an affinity purified rabbit polyclonal antibody, raised against a peptide mapping near the carboxy terminus of human PPARgamma. Immunogen: A synthetic peptide mapping near the carboxy terminus of human PPARgamma. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PPARgamma are readily searchable from our website. Different antibodies against the same target such as PPARgamma may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Adipose Tissue, Bone, Brain, Connective Tissue, Heart, Intestine, Kidney, Liver, Lung, Vascular tissues are correlated with this protein. Atherosclerosis, Diabetes Mellitus, Diabetes Mellitus, Type 2, Fatty Liver, Hypertension, Inflammation, Insulin Resistance, Metabolic Diseases, Necrosis, Obesity are some of the diseases may be linked to PPARgamma (C15) Antibody.