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anti-PPAPDC1A antibody product blog

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Posted on 2015-06-27 17:40:29 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; PPAPDC1A; anti-PPAPDC1A antibody;
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The PPAPDC1A ppapdc1a (Catalog #MBS150825) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PPAPDC1A Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s PPAPDC1A can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB), Immunofluorescence (IF).
PPAPDC1A antibody can be used for detection of PPAPDC1A by Western blot at 1 mug/mL. For immunofluorescence start at 20 mug/mL. Researchers should empirically determine the suitability of the PPAPDC1A ppapdc1a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The PPAPDC1A ppapdc1a product has the following accession number(s) (GI #73611920) (NCBI Accession #NP_001025230) (Uniprot Accession #Q5VZY2). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the PPAPDC1A Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of PPAPDC1A in human brain tissue lysate with PPAPDC1A antibody at 1 μg/mL in (A) the absence and (B) the presence of blocking peptide.)
Western Blot (WB) PPAPDC1A.

Immunofluorescence (IF) (Immunofluorescence of PPAPDC1A in human brain tissue with PPAPDC1A antibody at 20 μg/mL.)
Immunofluorescence (IF) PPAPDC1A.

PPAPDC1A Antibody: Phosphatidate phosphatase (PAP) plays important role in lipid-signaling metabolism in eukaryotic cells. Two distinct types of PAP (PAP1 and PAP2) activity have been distinguished by their subcellular localization and differential sensitivity to N-ethylmaleimide(NEM) and Mg2+. A yeast diacylglycerol pyrophosphate (DGPP) phosphatase (DPP1) and mammalian DGPP phosphatase (PAP2) have been identified as Mg2+-independent and NEM-insensitive membrane-associated. PPAPDC1A (also known as DPPL2) and PPAPDC1B (DPPL1) form a novel type of Mg2+-independent and NEM-sensitive mammalian phosphatidate phosphatase showing broad substrate specificity. PPAPDC1A is preferentially expressed in endothelial cells. Studies of PPAPDC1A and PAP activity suggest that they may play a role in angiogenesis.

Conjugate: Unconjugated
Immunogen: PPAPDC1A antibody was raised against a 14 amino acid synthetic peptide near the carboxy terminus of human PPAPDC1A.
Buffer: PPAPDC1A Antibody is supplied in PBS containing 0.02% sodium azide. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PPAPDC1A are readily searchable from our website. Different antibodies against the same target such as PPAPDC1A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.
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