anti-PP2Ac antibody product blog
Tags: Antibody; Monoclonal Antibody; PP2Ac / PPP2CA; anti-PP2Ac antibody; PP2Ac;
The PP2Ac ppp2ca (Catalog #MBS245334) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Mouse Monoclonal [clone P6C7] (IgG2b,k) to Human PP2Ac / PPP2CA reacts with Human and may cross-react with other species as described in the data sheet. MyBioSource\'s PP2Ac / PPP2CA can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), Western Blot (WB), Immunoprecipitation (IP), ELISA (EIA).ELISA, IHC-P (15 ug/ml), IP, WB (1:250 - 1:1000)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the PP2Ac ppp2ca for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PP2Ac ppp2ca product has the following accession number(s) (GI #4506017) (NCBI Accession #NP_002706.1) (Uniprot Accession #P67775). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Mouse Monoclonal [clone P6C7] (IgG2b,k) to Human PP2Ac / PPP2CA with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-PPP2CA / PP2Ac antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 15 ug/ml.)
Western Blot (WB) (Mouse liver cytosol extract was resolved by electrophoresis, transferred to PVDF membrane and probed with anti-PP2Ca(1:250). Proteins were visualized using a goat anti-mouse secondary antibody conjugated to HRP and a DAP detection system. Arrow indicates PP2Ca(~43kD).)
Protein phosphatase 2A alpha (PPP2CA), is a PP2A type serine/threonine phosphatase. PP2A members are composed of a common heterodimeric core enzyme (a catalytic subunit C and a constant regulatory subunit PR65 or A) that associates with a wide variety of regulatory subunits (subunit B). PPP2CA is a catalytic subunit that plays a role in transcription, translation, cell cycle control, and the regulation of most major metabolic pathways.
Target Species: Human
Immunogen Description: Recombinant human PP2Ckappa protein. Immunogen Type: Recombinant protein
Immunogen: PP2Ac / PPP2CA antibody was raised against recombinant human PP2Ckappa protein. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PP2Ac are readily searchable from our website. Different antibodies against the same target such as PP2Ac may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.