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anti-PLIN1 antibody product blog

Posted on 2014-09-05 01:35:33 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; anti-PLIN1 antibody; PLIN1; Perilipin;
The PLIN1 plin1 (Catalog #MBS534338) is an Antibody produced from Guinea Pig and is intended for research purposes only. The product is available for immediate purchase. The Perilipin antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s Perilipin can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC) Formalin/Paraffin, Western Blot (WB).
IHC-F: 1:100-200
IHC-P: 1:100-1:200
WB: 1:2,000. Researchers should empirically determine the suitability of the PLIN1 plin1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The PLIN1 plin1 product has the following accession number(s) (GI #3041771) (NCBI Accession #BAA25420.1) (Uniprot Accession #O60240). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Guinea Pig polyclonal Perilipin antibody.

PLIN1 plin1

Biological Significance: Perilipins build a family of phosphoproteins. The predominant forms in adipocytes, perilipin An and B arise by alternative RNA splicing from a single gene, generating polypeptides of 57 and 46 kDa, respectively. The N-terminus, however, remains unchanged. The antiserum reacts specifically with perilipins (An and B) located at the surface of intracellular storage lipid droplets present e.g. in the adrenal gland, adipocytes of white and brown adipose tissue and cultured cells such as 3T3-L1 adipocytes and cultured steroidogenic adrenal cortical and Leydig cells. Biohazard Information: This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.
Immunogen: Perilipin antibody was raised in guinea pig using duplicated N-terminus of perilipin as the immunogen. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PLIN1 are readily searchable from our website. Different antibodies against the same target such as PLIN1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Body Weight Changes, Dyslipidemias, Fatty Liver, Hyperinsulinism, Hypertriglyceridemia, Hypertrophy, Inflammation, Insulin Resistance, Obesity, Weight Loss are some of the diseases may be linked to Perilipin antibody. PLIN1 also interacts with the following gene(s): ABHD5, CAV1, CIDEC, FABP4, INS, LIPE, PNPLA2, PPARG, PPARGC1A, PRKACA. Adipose Tissue, Bone, Connective Tissue, Heart, Liver, Muscle, Skin, Testis, Uncharacterized Tissue, Vascular tissues are correlated with this protein. The following patways have been known to be associated with this gene.
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