|The PDE7A pde7a (Catalog #MBS240106) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human PDE7A reacts with Bat, Gibbon, Bovine, Dog, Xenopus, Gorilla, Human, Monkey, Orangutan, Rabbit
Predicted Reactivity: Mouse, Rat, Hamster (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s PDE7A can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin).
IHC-P (20 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antib.. Researchers should empirically determine the suitability of the PDE7A pde7a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDE7A pde7a product has the following accession number(s) (GI #334085277) (NCBI Accession #NP_001229247.1) (Uniprot Accession #Q13946). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human PDE7A with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-PDE7A antibody IHC of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
Phosphodiesterase 7A, a cAMP-specific phosphodiesterase, has been shown to affect memory, T-cell functioning and emesis and has been implicated in depression. Two isoforms (PDE7A1 and PDE7A2) which differ at their N-terminal region, have been reported.
Target Species: Human
Immunogen Description: Synthetic 17 amino acid peptide from N-terminus of human PDE7A. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Dog, Bat, Elephant, Panda, Rabbit, Opossum, Xenopus (100%). Immunogen Type: Synthetic peptide
Immunogen: PDE7A antibody was raised against synthetic 17 amino acid peptide from N-terminus of human PDE7A. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Bovine, Dog, Bat, Elephant, Panda, Rabbit, Opossum, Xenopus (100%); Mouse, Rat, Hamster, Turkey, Lizard (94%); Zebrafish (82%).
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PDE7A are readily searchable from our website. Different antibodies against the same target such as PDE7A may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.