anti-PDE11A4 antibody product blog
Tags: Antibody; Polyclonal Antibody; PDE11A4; anti-PDE11A4 antibody;
The PDE11A4 pde11a (Catalog #MBS540058) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The PDE11A4 Antibody Affinity Purified reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s PDE11A4 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), IMM, Western Blot (WB).Dot Blot: 1:10,000
ELISA: 1:10,000
Immunoprecipitation: 1:250
Western Blot: 1:500. Researchers should empirically determine the suitability of the PDE11A4 pde11a for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PDE11A4 pde11a product has the following accession number(s) (GI #15128482) (NCBI Accession #BAB62712.1) (Uniprot Accession #Q9HCR9). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Affinity Purified Phosphodiesterase 11A4 Antibody
Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides cAMP and cGMP. Catalyzes the hydrolysis of both cAMP and cGMP to 5\'-AMP and 5\'-GMP, respectively.
Immunogen: Synthetic peptide unique to PDE11A4 variant
Expression: Isoform 1 is present in prostate, pituitary, heart and liver. It is however not present in testis nor in penis, suggesting that weak inhibition by Tadalafil is not relevant (at protein level). Isoform 2 may be expressed in testis. Isoform 4 is expressed i. Molecular Function: Hydrolase, 3\', 5\'-cyclic-GMP phosphodiesterase activity, cGMP binding
Subcellular Location: Cytoplasm. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PDE11A4 are readily searchable from our website. Different antibodies against the same target such as PDE11A4 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Abnormalities, Multiple, Adenocarcinoma, Congenital Abnormalities, Disease Models, Animal, Heart Diseases, Hyperplasia, Hypertension, Infertility, Male, Memory Disorders, Precancerous Conditions are some of the diseases may be linked to PDE11A4 Antibody Affinity Purified. The following patways have been known to be associated with this gene. Brain, Muscle, Nerve, Prostate, Testis tissues are correlated with this protein.