|The PAK6 pak6 (Catalog #MBS240879) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Rabbit Polyclonal to Human PAK6 reacts with Bat, Gibbon, Bovine, Chicken, Dog, Gorilla, Horse, Human, Monkey, Mouse, Orangutan, Rabbit, Rat
Predicted Reactivity: Xenopus (at least 90% immunogen sequence identity) and may cross-react with other species as described in the data sheet. MyBioSource\'s PAK6 can be used in a range of immunoassay formats including, but not limited to, Immunohistochemistry (IHC - Paraffin), ELISA (EIA).
ELISA, IHC-P (10 ug/ml)
Usage: Immunohistochemistry: was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary anti.. Researchers should empirically determine the suitability of the PAK6 pak6 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PAK6 pak6 product has the following accession number(s) (GI #9910476) (NCBI Accession #NP_064553.1) (Uniprot Accession #Q9NQU5). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Rabbit Polyclonal to Human PAK6 with the following immunoassay(s):
Immunohistochemistry (IHC) (Anti-PAK6 antibody IHC of human testis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.)
PAK6, a PAK (STE20) type protein kinase, contains a N-terminal Cdc42/Rac interactive binding (CRIB) motif and a C-terminal kinase domain. The protein has been shown to bind to GTP-Cdc42 and GTP-Rac; however, in contrast to most PAKs, kinase activity was not stimulated by Cdc42 or Rac, but could be stimulated by androgen receptor (AR) binding. PAK6 protein also has been shown to bind to estrogen receptor alpha.
Target Species: Human
Immunogen Description: Synthetic 16 amino acid peptide from N-terminus of human PAK6. Immunogen Type: Synthetic peptide
Immunogen: PAK6 antibody was raised against synthetic 16 amino acid peptide from N-terminus of human PAK6. Percent identity with other species by BLAST analysis: Human, Gorilla, Orangutan, Gibbon, Monkey, Marmoset, Mouse, Rat, Bovine, Dog, Bat, Elephant, Panda, Horse, Rabbit, Sparrow, Chicken, Platypus (100%); Xenopus (94%); Goat (88%).
Antigen Modification: N-Terminus. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PAK6 are readily searchable from our website. Different antibodies against the same target such as PAK6 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results.