|The PAFAH1B3 pafah1b3 (Catalog #MBS606245) is an Antibody produced from Mouse and is intended for research purposes only. The product is available for immediate purchase. The Platelet-activating Factor Acetylhydrolase IB Subunit gamma (PAF Acetylhydrolase 29kD Subunit, PAF-AH 29kD Subunit, PAFAHG, PAFAH gamma Subunit, Platelet-activating Factor Acetylhydrolase IB gamma Subunit) reacts with Human, Mouse and may cross-react with other species as described in the data sheet. MyBioSource\'s Platelet-activating Factor Acetylhydrolase IB Subunit gamma can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB), Immunofluorescence (IF).
Suitable for use in Western Blot, Immunofluorescence and ELISA.
Dilution: Immunoflorescence: 25ug/ml
ELISA: Direct or sandwich. Researchers should empirically determine the suitability of the PAFAH1B3 pafah1b3 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The PAFAH1B3 pafah1b3 product has the following accession number(s) (GI #225543099) (NCBI Accession #NP_001139412.1) (Uniprot Accession #Q15102). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Cytosolic PAFAH IB is formed of three subunits, alpha (45kD), beta (30kD) and gamma (29kD). The catalytic activity of PAFAH IB resides in the beta and gamma subunits while the alpha subunit has regulatory activity. Trimer formation is not essential for the catalytic activity. Specifically, PAFAH subunit gamma inactivates platelet-activating factor by removing the acetyl group at the sn-2 position. It plays an important role during the development of the brain. In the adult, it is expressed in brain, skeletal muscle, kidney, thymus, spleen, colon, testis, ovary and peripheral blood leukocytes. In the fetus, highest expression occurs in the brain.
Immunogen: Partial recombinant human PAFAH subunit gamma (1-232) (GST). In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing PAFAH1B3 are readily searchable from our website. Different antibodies against the same target such as PAFAH1B3 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. PAFAH1B3 also interacts with the following gene(s): PAFAH1B1, PAFAH1B2. The following patways have been known to be associated with this gene. Abnormalities, Multiple, Bipolar Disorder, Hydrocephalus, Inflammation, Nervous System Diseases, Nervous System Malformations, Schizophrenia, Translocation, Genetic are some of the diseases may be linked to Platelet-activating Factor Acetylhydrolase IB Subunit gamma (PAF Acetylhydrolase 29kD Subunit, PAF-AH 29kD Subunit, PAFAHG, PAFAH gamma Subunit, Platelet-activating Factor Acetylhydrolase IB gamma Subunit).