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anti-p53 antibody product blog

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Posted on 2013-10-06 20:01:16 by mybiosource_staff
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Tags: Antibody; anti-p53 antibody; p53;
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The p53 tp53 (Catalog #MBS330073) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. MyBioSource\'s p53 can be used in a range of immunoassay formats including, but not limited to, ELISA (EIA), Western Blot (WB).
ELISA, 1: 2500 WB, 1:2500. Researchers should empirically determine the suitability of the p53 tp53 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The p53 tp53 product has the following accession number(s) (GI #23491729) (NCBI Accession #BAC16799.1) (Uniprot Accession #P04637). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the Anti-p53 (human), HRP with the following immunoassay(s):
Testing Data
Testing Data p53.

This antibody was developed and affinity purified using a peptide based on human p53 sequence (25-40 aa). The antibody (ICP-7110) was conjugated to peroxidase (HRP) via reductive amination. It was tested to detect the human p53 specifically in human cell and tissue. Direct labeling of peroxdase of the primary antibody was believed to avoid the effect of IgG (50-60 kd) signal due to the use of secondary antibodies.

Immunogen: Human p53 peptide (15-40aa) KLH conjugates. Conjugation: reductive amination. Ab/HRP ratio=1/2. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing p53 are readily searchable from our website. Different antibodies against the same target such as p53 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Breast Neoplasms, Carcinoma, Carcinoma, Small Cell, Carcinoma, Squamous Cell, Cell Transformation, Neoplastic, Colorectal Neoplasms, Glioma, Neoplasm Metastasis, Urogenital Neoplasms, Urologic Neoplasms are some of the diseases may be linked to Anti-p53 (human), HRP. Blood, Brain, Kidney, Liver, Lung, Lymph, Muscle, Prostate, Skin, Vascular tissues are correlated with this protein.
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