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anti-OAS1 antibody product blog

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Posted on 2014-09-01 01:19:06 by mybiosource_staff
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Tags: Antibody; Polyclonal Antibody; OAS1; anti-OAS1 antibody;
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The OAS1 oas1 (Catalog #MBS129033) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The OAS1 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s OAS1 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB), Immunohistochemistry (IHC), Immunofluorescence (IF).
WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:50 - 1:100. Researchers should empirically determine the suitability of the OAS1 oas1 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The OAS1 oas1 product has the following accession number(s) (GI #296439492) (NCBI Accession #P00973.4) (Uniprot Accession #P00973). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:


Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the OAS1 Polyclonal Antibody with the following immunoassay(s):
Immunofluorescence (IF) (Immunofluorescence analysis of HeLa cell using OAS1 antibody.)
Immunofluorescence (IF) OAS1.

This gene encodes a member of the 2-5A synthetase family, essential proteins involved in the innate immune response to viral infection. The encoded protein is induced by interferons and uses adenosine triphosphate in 2\'-specific nucleotidyl transfer reactions to synthesize 2\',5\'-oligoadenylates (2-5As). These molecules activate latent RNase L, which results in viral RNA degradation and the inhibition of viral replication. The three known members of this gene family are located in a cluster on chromosome 12. Mutations in this gene have been associated with host susceptibility to viral infection. Alternatively spliced transcript variants encoding different isoforms have been described.

Species: Human
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human OAS1
Calculated Molecular Weight: 46kDa. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing OAS1 are readily searchable from our website. Different antibodies against the same target such as OAS1 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. Blood, Bone, Brain, Kidney, Liver, Lung, Mouth, Muscle, Prostate, Uterus tissues are correlated with this protein. Carcinoma, Carcinoma, Squamous Cell, Diabetes Mellitus, Type 1, Disease Models, Animal, Inflammation, Influenza, Human, Liver Diseases, Necrosis, Neoplasms, Experimental, Virus Diseases are some of the diseases may be linked to OAS1 Polyclonal Antibody.
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