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anti-NTRK2 antibody product blog

Posted on 2013-08-13 21:01:43 by mybiosource_staff
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Tags: Antibody; NTRK2; Polyclonal Antibody; anti-NTRK2 antibody;
The NTRK2 ntrk2 (Catalog #MBS125105) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The NTRK2 Polyclonal Antibody reacts with Human, Mouse, Rat and may cross-react with other species as described in the data sheet. MyBioSource\'s NTRK2 can be used in a range of immunoassay formats including, but not limited to, Western Blot (WB).
WB: 1:500 - 1:2000. Researchers should empirically determine the suitability of the NTRK2 ntrk2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.

The NTRK2 ntrk2 product has the following accession number(s) (GI #2497560) (NCBI Accession #Q16620.1) (Uniprot Accession #Q16620). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.

To buy or view more detailed product information and pricing, please click on the technical datasheet page below:

Please refer to the product datasheet for known applications of a given antibody. We\'ve tested the NTRK2 Polyclonal Antibody with the following immunoassay(s):
Western Blot (WB) (Western blot analysis of extracts of U-251MG cells, using NTRK2 antibody at 1:1000 dilution.
Secondary antibody: HRP Goat Anti-Mouse IgG (H+L) (MBS128212) at 1:10000 dilution.
Lysates/proteins: 25ug per lane.
Blocking buffer: 3% nonfat dry milk in TBST.
Detection: ECL Enhanced Kit.
Exposure time: 90s.)
Western Blot (WB) NTRK2.

This gene encodes a member of the neurotrophic tyrosine receptor kinase (NTRK) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Signalling through this kinase leads to cell differentiation. Mutations in this gene have been associated with obesity and mood disorders. Alternate transcriptional splice variants encoding different isoforms have been found for this gene.

Species: Human
Immunogen: Recombinant Protein. Immunogen: Recombinant protein of human NTRK2
Calculated Molecular Weight: 53kD. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NTRK2 are readily searchable from our website. Different antibodies against the same target such as NTRK2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. The following patways have been known to be associated with this gene. NTRK2 also interacts with the following gene(s): BDNF, GIPC1, NGFR, NTF3, NTF4, PLCG1, SH2B1, SHC1, SHC2, SHC3. Cardiovascular Diseases, Disease Models, Animal, Inflammation, Learning Disorders, Memory Disorders, Nerve Degeneration, Nervous System Diseases, Neuroblastoma, Pain, Seizures are some of the diseases may be linked to NTRK2 Polyclonal Antibody. Bone, Brain, Ear, Embryonic Tissue, Eye, Lung, Mouth, Muscle, Nerve, Ovary tissues are correlated with this protein.
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