anti-NOS2 antibody product blog
Tags: Antibody; Nitrotyrosine; Polyclonal Antibody; anti-NOS2 antibody; NOS2;
The NOS2 nos2 (Catalog #MBS617411) is an Antibody produced from Rabbit and is intended for research purposes only. The product is available for immediate purchase. The Nitrotyrosine (nTyr) reacts with Mammal and may cross-react with other species as described in the data sheet. MyBioSource\'s Nitrotyrosine can be used in a range of immunoassay formats including, but not limited to, ELISA (EL/EIA), Western Blot (WB).Suitable for use in ELISA and Western Blot.
Dilution: Western Blot: 1-5ug/ml
ELISA: 1:10,000-1:50,000 using 50-100ng control nitrated proteins/well. Researchers should empirically determine the suitability of the NOS2 nos2 for an application not listed in the data sheet. Researchers commonly develop new applications and it is an integral, important part of the investigative research process.
The NOS2 nos2 product has the following accession number(s) (GI #116003827) (NCBI Accession #NP_001070267.1) (Uniprot Accession #Q27995). Researchers may be interested in using Bioinformatics databases such as those available at The National Center for Biotechnology Information (NCBI) website for more information about accession numbers and the proteins they represent. Even researchers unfamiliar with bioinformatics databases will find the NCBI databases to be quite user friendly and useful.
To buy or view more detailed product information and pricing, please click on the technical datasheet page below:
Nitric oxide (NO) and reacti04.10.07ve oxygen species (ROS) are important mediators that produce harmful or protective functions. NO can react with superoxide anions (O2-), yielding the toxic oxidizing agent peroxynitrite (ONOO-). Peroxynitrite induces nitration of tyrosine residues leading to changes in protein structure and function, and alterations in signaling pathways. Antibodies to nitrotyrosine have been used to monitor the status of peroxynitrite-induced modification of proteins.
Immunogen: Nitrated KLH. In general, we may offer more than one antibody to a given target to enable options for the researcher. Available antibodies recognizing NOS2 are readily searchable from our website. Different antibodies against the same target such as NOS2 may be optimized or tested for different applications and species. This enables researchers to select the option that may be best for their model system, to screen more than antibody to determine which one may be best for their model system, as well as to use more than one antibody to follow up on and validate their results. Endotoxemia, Hypertension, Inflammation, Intestinal Diseases, Kidney Diseases, Liver Diseases, Necrosis, Reperfusion Injury, Sepsis, Shock, Septic are some of the diseases may be linked to Nitrotyrosine (nTyr). Extraembryonic Tissue, Intestine, Muscle, Ovary, Uncharacterized Tissue tissues are correlated with this protein. The following patways have been known to be associated with this gene.